Clevudine

Mfr.No.	T6446
Description	Clevudine (Levovir) is a synthetic pyrimidine analogue with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DNA (cccDNA), therefore the patient is less likely to have a relapse after treatment is discontinued.
Alternative Names	Levovir
Molecular Formula	C10H13FN2O5
Signaling Pathways	DNA Damage/DNA Repair, Microbiology/Virology, Cell Cycle/Checkpoint
Smiles	F(CH)1(CH)(O(CH)(CO)(CH)1O)N2C(=O)NC(=O)C(C)=C2
Cas Number	163252-36-6
Molecular Weight	260.22
Target	DNA/RNA Synthesis, HBV

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SKU	Supplier No.	Size	Your price
BHB20434573	T6446	1 mL	$80	Add to Cart
BHB20434573	T6446	5 mg	$47	Add to Cart
BHB20434573	T6446	10 mg	$72	Add to Cart
BHB20434573	T6446	25 mg	$128	Add to Cart
BHB20434573	T6446	50 mg	$207	Add to Cart
BHB20434573	T6446	100 mg	$369	Add to Cart