CID 2011756

Mfr.No.	SIH-438
Alternative Names	CID-2011756, 5-(3-Chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide
Appearance	White to beige solid
Function	PKD kinase inhibitor
Inchi	InChI=1S/C22H21ClN2O3/c23-18-3-1-2-17(14-18)20-8-9-21(28-20)22(26)24-19-6-4-16(5-7-19)15-25-10-12-27-13-11-25/h1-9,14H,10-13,15H2,(H,24,26)
Inchikey	XQJWTJLJEYIUDZ-UHFFFAOYSA-N
Mode Of Action	Inhibitor
Molecular Formula	C22H21ClN2O3
Pubchem Cid	2011756
Research Area	Cell Signaling ; Cancer ; Apoptosis ; Cancer Growth Inhibitors ; Tyrosine Kinase Inhibitors
Safety Phrases	Classification: Acute toxicity, Oral(Category 4) Eye irritation(Category 2A) Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Hazard statements: H302 Harmful if swallowed. H319 Causes serious eye irritation. Precautionary statements: P305 + P351 + P338 IF IN EYES: Rinse cautiousl y with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Smiles	C1COCCN1CC2=CC=C(C=C2)NC(=O)C3=CC=C(O3)C4=CC(=CC=C4)Cl
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	638156-11-3
Molecular Weight	396.9
Scientific Background	CID 2011756 is a specific, ATP-competitive protein kinase D inhibitor. It is also cell permeable.
Solubility	Soluble to 50 mM in DMSO
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Sharlow E.R., et al. (2011) PloS One 6(10): e25134.

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