CHIR-99021 HCl

Mfr.No.	T2310L
Description	CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3alpha/beta, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivity over CDC2, ERK2, and other protein kinases. Additionally, CHIR-99021 HCl serves as a robust activator of the Wnt/beta-catenin signaling pathway. Moreover, it exhibits the ability to enhance self-renewal in both mouse and human embryonic stem cells. Furthermore, CHIR-99021 HCl induces autophagy (1) (2) (3).
Alternative Names	CT99021 HCl
Molecular Formula	C22H19Cl3N8
Signaling Pathways	PI3K/Akt/mTOR signaling, Stem Cells
Smiles	Cl.NCC1=CN=C(C=C1)NCCNC=2N=CC(C3=NC=C(N3)C)=C(N2)C=4C=CC(Cl)=CC4Cl
Cas Number	1797989-42-4
Molecular Weight	501.8
Target	GSK-3

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SKU	Supplier No.	Size	Your price
BHB20412920	T2310L	1 mL	$78	Add to Cart
BHB20412920	T2310L	1 mg	$30	Add to Cart
BHB20412920	T2310L	2 mg	$44	Add to Cart
BHB20412920	T2310L	5 mg	$70	Add to Cart
BHB20412920	T2310L	10 mg	$97	Add to Cart
BHB20412920	T2310L	25 mg	$166	Add to Cart
BHB20412920	T2310L	50 mg	$253	Add to Cart
BHB20412920	T2310L	100 mg	$490	Add to Cart
BHB20412920	T2310L	200 mg	$711	Add to Cart
BHB20412920	T2310L	500 mg	$1080	Add to Cart