CCR4 antagonist 2

Mfr.No.	T10713
Description	CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits Treg trafficking into the Tumor Microenvironment without suppressing the number of Treg in healthy tissues. CCR4 antagonist 2 (Compound 31) exhibits IC50 values of Ca2+flux and (chemotaxis) CTX are 40 nM and 70 nM, respectively.
Molecular Formula	C26H28Cl2N6O
Signaling Pathways	Membrane transporter/Ion channel, Metabolism
Smiles	(CH)(C)(N1C=2C(C(CN)=N1)=NC=C(N2)C=3C(CH)(C)(CH)(CC3)N4(CH)(CO)CCC4)C5=C(Cl)C=C(Cl)C=C5
Cas Number	2206788-99-8
Molecular Weight	511.45
Target	Calcium Channel

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SKU	Supplier No.	Size	Your price
BHB20401437	T10713	25 mg	$2720	Add to Cart
BHB20401437	T10713	50 mg	$3580	Add to Cart
BHB20401437	T10713	100 mg	$4900	Add to Cart