CAY10747

Mfr.No.	T36197
Description	CAY10747 is an inhibitor of the protein-protein interaction between heat shock protein 90 (Hsp90) and cell division cycle 37 (Cdc37) and a derivative of celastrol .1It decreases protein levels of the Hsp90-Cdc37 complex and the Hsp90-Cdc37 clients phosphorylated Akt and Cdk4 in A549 cells when used at a concentration of 5 uM. CAY10747 inhibits proliferation of A549, MCF-7, HOS, and HepG2 cells (IC50s = 0.41, 0.64, 0.9, and 0.94 uM, respectively) and induces apoptosis in A549 cells.
Molecular Formula	C42H48FNO6
Signaling Pathways	Others
Smiles	C(C)12(C)(C)((C)3((C)(C)(CC1)CC(C)(C(OCCCOC(/C=C(CN)/C4=CC=C(F)C=C4)=O)=O)(C)C3)(H))CC(C)5(C)C2=CC=C6C5=CC(=O)C(O)=C6C
Cas Number	2413849-81-5
Molecular Weight	681.83
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20425556	T36197	1 mg	$145	Add to Cart
BHB20425556	T36197	5 mg	$653	Add to Cart
BHB20425556	T36197	10 mg	$1080	Add to Cart
BHB20425556	T36197	25 mg	$2350	Add to Cart