CAPE

Mfr.No.	SIH-263
Alternative Names	2-Phenylethyl (2E)-3-(3,4-dihydroxyphenyl)acrylate, Caffeic acid phenethyl ester
Appearance	Off-White Solid
Function	NFkB Inhibitor
Inchi	InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
Inchikey	SWUARLUWKZWEBQ-VQHVLOKHSA-N
Mode Of Action	Inhibitor
Molecular Formula	C17H16O4
Pubchem Cid	5281787
Research Area	Cancer ; Apoptosis
Safety Phrases	Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H315-H319-H335 Precautionary Phrases: P261-P305 + P351 + P338
Smiles	C1=CC=C(C=C1)CCOC(=O)/C=C/C2=CC(=C(C=C2)O)O
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	104594-70-9
Molecular Weight	284.31
Scientific Background	CAPE , an active component of propolis from honeybee hives is known to have antioxidant, antimitogenic, anticarcinogenic, anti-inflammatory and antiviral properties (1). It specifically inhibits NF-κB activation and inhibits the growth of transformed cells (1). Also suppresses lipid peroxidation and inhibits ornithine decarboxylase, protein tyrosine kinase and lipoxygenase activities.
Solubility	Soluble to 100 mM in DMSO, acetone, ethanol, methanol, acetonitrile
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Natarajan K., Singh S., Burke T.R., Grunberger D., Aggarwal B.B. (1996) Proc Natl Acad Sci USA. 93(17): 9090-9095.

Have you used this product?

Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900085-1	SIH-263-50MG	50 mg	$65		Add to Cart
BHB11900085-2	SIH-263-250MG	250 mg	$265		Add to Cart