C6 D-threo Ceramide (d18:1/6:0)

Mfr.No.	T37565
Description	C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 uM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 uM but induces cell death at concentrations greater than 5 uM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate in EL4 T cells when used at a concentration of 10 uM.
Molecular Formula	C24H47NO3
Signaling Pathways	Others
Smiles	(CH)(NC(CCCCC)=O)((CH)(/C=C/CCCCCCCCCCCCC)O)CO
Cas Number	189894-79-9
Molecular Weight	397.63
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20426687	T37565	1 mg	$489		Add to Cart