C18 Globotriaosylceramide (d18:1/18:0)

Mfr.No.	T37439
Description	C18 globotriaosylceramide is an endogenous sphingolipid found in mammalian cell membranes that is synthesized from lactosylceramide . It inhibits aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate (PMA; 10008014) when used at a concentration of 1 uM. C18 globotriaosylceramide acts as a receptor for Shiga toxin in B cell-derived Raji cells and THP-1 monocytes. It accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme alpha-galactosidase A. C18 globotriaosylceramide also accumulates in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease.
Molecular Formula	C54H101NO18
Signaling Pathways	Others
Smiles	CCCCCCCCCCCCCCCCCC(=O)N(CH)(CO(CH)1O(CH)(CO)(CH)(O(CH)2O(CH)(CO)(CH)(O(CH)3O(CH)(CO)(CH)(O)(CH)(O)(CH)3O)(CH)(O)(CH)2O)(CH)(O)(CH)1O)(CH)(O)C=CCCCCCCCCCCCCC
Cas Number	69283-33-6
Molecular Weight	1052.391
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20426587	T37439	1 mg	-		Add to Quote