Bischloroanthrabenzoxocinone

Mfr.No.	T37408
Description	Bacterial type II fatty acid synthesis (FAS-II) is mediated by a series of enzymes, each of which may be targeted by potential antibiotics. Bischloroanthrabenzoxocinone (BABX) is an inhibitor of FAS-II, blocking fatty acid synthesis in S. aureus and E. coli with IC50 values of 11.4 and 35.3 ug/ml, respectively. It inhibits the growth of S. aureus and permeable E. coli strains with minimum inhibitory concentrations ranging from 0.2-0.4 ug/ml. BABX also displays binding to liver X receptors (LXRs), inhibiting agonist binding in an LXRalpha-scintillation proximity assay (IC50 = 10 uM).
Molecular Formula	C28H24Cl2O7
Signaling Pathways	Others
Smiles	(H)(C)12O(C)(C)(Cc3cc4c(C(=O)c5c(O)c(Cl)c(O)c(Cl)c5C4(C)C)c(O)c13)Oc1cc(OC)cc(C)c21 \|TLB:25:27:37.29.28:2,30:29:2:27.5.6,35:37:2:27.5.6\|
Cas Number	866022-28-8
Molecular Weight	543.39
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20426561	T37408	500 ?g	$850		Add to Cart