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Barbadin

SKU : BHB20407877

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Description
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Mfr.No.	T14498
Description	Barbadin is a novel and specific inhibitor of beta-arrestin/beta2-adaptin interaction with an IC50 value of 19.1 uM for beta-arestin1 and 15.6 uM for beta-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC neurons and weight loss. Barbadin potentiates the long-term effects of lorcaserin on POMC neurons and weight loss, blocks agonist-promoted endocytosis of prototypic beta2-adrenergic, V2-vasopressin, and angiotensin-II-1 receptors, and may be useful in the study of obesity.
Molecular Formula	C19H15N3OS
Signaling Pathways	GPCR/G Protein
Smiles	NN1C=NC2=C(C(=CS2)C2=CC=C(CC3=CC=CC=C3)C=C2)C1=O
Cas Number	356568-70-2
Molecular Weight	333.41
Target	Arrestin

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SKU	Supplier No.	Size	Your price	Quantity
BHB20407877	T14498	1 mg	$199		Add to Cart

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Barbadin

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