AZD5582 dihydrochloride

Mfr.No.	T36201
Description	Dimeric Smac mimetic; potent inhibitor of X-linked (XIAP) and cellular (cIAP) inhibitor of apoptosis protein (IC50 values are 15, 15 and 21 nM for XIAP, cIAP1 and cIAP2 respectively). Binds to the BIR3 domain of XIAP to prevent interaction with caspase-9. Causes degradation of cIAP1 and cIAP2 and induces apoptosis in MDA-MB-231 breast cancer cells. Causes tumor regression in MDA-MB-231 xenograft-bearing mice.
Alternative Names	AZD 5582 dihydrochloride
Molecular Formula	C58H80Cl2N8O8
Signaling Pathways	Others
Smiles	Cl.Cl.CN(CH)(C)C(=O)N(CH)(C1CCCCC1)C(=O)N1CCC(CH)1C(=O)N(CH)1(CH)(Cc2ccccc12)OCCCCCCO(CH)1Cc2ccccc2(CH)1NC(=O)(CH)1CCCN1C(=O)(CH)(NC(=O)(CH)(C)NC)C1CCCCC1
Cas Number	1883545-51-4
Molecular Weight	1088.23
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20425561	T36201	10 mg	$975		Add to Cart