Afeletecan free base

Mfr.No.	T23654
Description	Afeletecan is a water-soluble camptothecin derivative. Afeletecan stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Both the initial cleavage reaction and religation steps are inhibited and subsequent collision of the replication fork with the cleaved strand of DNA results in inhibition of DNA replication, double-strand DNA breakage, and triggering of apoptosis.
Alternative Names	Afeletecan
Molecular Formula	C45H49N7O11S
Signaling Pathways	Others
Smiles	O(C((CH)(NC((CH)(CC1=CN=CN1)NC(NC2=CC=C(O(CH)3(CH)(O)(CH)(OC)(CH)(O)(CH)(C)O3)C=C2)=S)=O)C(C)C)=O)(C)4(CC)C5=C(C(=O)N6C(=C5)C=7C(C6)=CC=8C(N7)=CC=CC8)COC4=O
Cas Number	215604-75-4
Molecular Weight	895.98
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20413482	T23654	25 mg	$1520		Add to Cart