Adavosertib Liposomes, Formulation WD4

Mfr.No.	DLL-0005, DLL-0005-A1-2ML, DLL-0005-A1-10ML
Description	PEGylated liposomes containing Wee-1 kinase inhibitor adavosertib (MK1775; AZD1775), remote loaded by an ammonium sulfate gradient. The lipid composition of the liposomes is the same as Doxil. Sterile filtered and supplied ready for use in preclinical studies in rodents or in vitro. Adavosertib is a potent, ATP-competitive Wee-1 kinase inhibitor, which hinders the G2 DNA damage response checkpoint and is reported to enhance cytotoxic effects of several compounds including 5-FU and NSC 613327. For preclinical research use only.
Average Size	70-120 nm
Hydration Solution	250 mM Ammonium Sulfate, pH 5.5
External Solution	WD4
Concentration	1.0 mg/mL
Concentration Total Lipid	27.2 mM
Composition	HSPC/Chol/DSPE-mPEG2000 (56.2/38.5/5.3, mol/mol)
Types of Liposomes	Drug Loaded Liposomes

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Combination SKU	Supplier No.	Volume	Your price	Quantity
BHB19400003-1	DLL-0005-A1-2ML	2mL	$995		Add to Cart
BHB19400003-2	DLL-0005-A1-10ML	10mL	$4995		Add to Cart