9(Z),11(E),13(E)-Octadecatrienoic Acid

Mfr.No.	T36698
Description	9(Z),11(E),13(E)-Octadecatrienoic Acid (alpha-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. alpha-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, alpha-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARgamma. In DLD-1 cells supplemented with alpha-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 uM. It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 uM for different isoforms of the enzymes.
Molecular Formula	C18H30O2
Signaling Pathways	Others
Smiles	CCCCC=CC=CC=C/CCCCCCCC(O)=O
Cas Number	506-23-0
Molecular Weight	278.436
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20425952	T36698	1 mg	$143	Add to Cart
BHB20425952	T36698	5 mg	$623	Add to Cart
BHB20425952	T36698	10 mg	$1090	Add to Cart