6-Formylindolo(3,2-b)carbazole

Mfr.No.	SIH-383
Alternative Names	Indolo[3,2-b]carbazole-6-carbaldehyde, FICZ
Appearance	Yellow solid
Function	Ah receptor ligand
Inchi	InChI=1S/C19H10N2O/c22-10-14-18-12-6-2-4-8-16(12)20-17(18)9-13-11-5-1-3-7-15(11)21-19(13)14/h1-10H
Inchikey	OTWFDHQTFRXSAK-UHFFFAOYSA-N
Mode Of Action	Ligand
Molecular Formula	C19H12N2O
Pubchem Cid	22245026
Research Area	Cell Signaling
Safety Phrases	Classification: Caution. Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25 - Avoid contact with skin and eyes
Smiles	C1=CC=C2C(=C1)C3=CC4=NC5=CC=CC=C5C4=C(C3=N2)C=O
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	172922-91-7
Molecular Weight	284.3
Scientific Background	A tryptophan-derived, high affinity aryl hydrocarbon receptor ligand (Kd=7x10-11 M). Proposed to be an endogenous AhR ligand. Induces rapid and transient expression of cytochrome P450-1A1 (CYP1A1) in human cells at 100 pM.
Solubility	Soluble in DMSO (10 mg/ml)
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Wei Y.D., et al. (1998) Chem. Biol. Interact. 110(1-2): 39-55. 2. Rannug U., et al. (1995) Chem. Biol. Drug. Des. 2(12): 841-855. 3. Rannug A., et al. (1987) J. Biol. Chem. 262(32): 15422-7.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900171-1	SIH-383-100UG	100 ug	$99		Add to Cart
BHB11900171-2	SIH-383-500UG	500 ug	$410		Add to Cart