Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
Specificity
Natural and recombinant Rat Tumor necrosis factor receptor superfamily member 1B
"Molecular cloning and cellular expression of TNFR2 in rat dorsal root ganglion." Li Y., Ji A., Schafer M.K. Submitted (2003-07) to the EMBL/GenBank/DDBJ databases
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