ELISA Kit for Rat Translocator protein

Mfr.No.	E14158r
Alternative Names	Mitochondrial benzodiazepine receptor ; PKBS ; Peripheral-type benzodiazepine receptor ; PBR ; Bzrp ; Mbr
Categories	Elisa
Function	Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme. Plays a role in the transport of cholesterol across mitochondrial membranes in steroidogenic cells.
Specificity	Natural and recombinant Rat Translocator protein
Subcellular Location	Mitochondrion membrane Multi-pass membrane protein
Detection Range	0.312-20ng/mL
Entryname	TSPO_RAT
Method Type	Sandwich
Platform	PF03073
Protein Name	Translocator protein
Sensitivity	0.16ng/mL
Sequence	50: MSQSWVPAVG ; LTLVPSLGGF ; MGAYFVRGEG ; LRWYASLQKP ; SWHPPRWTLA ; 100: PIWGTLYSAM ; GYGSYIIWKE ; LGGFTEEAMV ; PLGLYTGQLA ; LNWAWPPIFF ; 150: GARQMGWALV ; DLMLVSGVAT ; ATTLAWHRVS ; PPAARLLYPY ; LAWLAFATML ; 169: NYYVWRDNSG ; RRGGSRLTE
Sequence Length	169
String	P16257
Sub Unit	Interacts with BZRAP1 (By similarity). Interacts with MOST-1 (By similarity). May interact with STAR.

Reference	1. "Molecular cloning and expression of cDNA encoding a peripheral-type benzodiazepine receptor." Sprengel R., Werner P., Seeburg P.H., Mukhin A.G., Santi M.R., Grayson D.R., Guidotti A., Krueger K.E. J. Biol. Chem.264:20415-20421(1989) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION tissue: Adrenal gland. 2. "Structure of the rat gene encoding the mitochondrial benzodiazepine receptor." Casalotti S.O., Pelaia G., Yakovlev A.G., Csikos T., Grayson D.R., Krueger K.E. Gene121:377-382(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] strain: Wistar. 3. "In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography." Ozaki H., Zoghbi S.S., Hong J., Verma A., Pike V.W., Innis R.B., Fujita M. Synapse64:649-653(2010) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PROTOPORPHYRIN BINDING

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811697	E14158r	96T	$796		Add to Cart