JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Sortilin

SKU : BHE13810758

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E9893r
Alternative Names	Glycoprotein 110 ; Gp110 ; Neurotensin receptor 3 ; NTR3
Categories	Elisa
Function	Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.
Specificity	Natural and recombinant Rat Sortilin
Subcellular Location	Membrane Single-pass type I membrane protein Endoplasmic reticulum membrane Single-pass type I membrane protein Endosome membrane Single-pass type I membrane protein Golgi apparatus Golgi stack membrane Single-pass type I membrane protein Lysosome membrane Single-pass type I membrane protein Nucleus membrane Single-pass type I membrane protein Cell membrane Single-pass type I membrane protein Extracellular side Lysosome membrane Single-pass type I membrane protein Localized to membranes of the endosomes, Golgi stack, lysosomes and nucleus. Localization to the plasma membrane in adipocytes is enhanced by insulin (By similarity). Localized to the endoplasmic reticulum and the plasma membrane. Also found in SLC2A4/GLUT4 storage vesicles (GSVs) in adipocytes.
Detection Range	0.156-10ng/mL
Entryname	SORT_RAT
Method Type	Sandwich
Platform	PF02012
Protein Name	Sortilin
Sensitivity	0.054ng/mL
Sequence	50: MERPRGAADG ; LLRWPLGLLL ; LLQLLPPAAV ; GQDRLDAPPP ; PAPPLLRWAG ; 100: PVGVSWGLRA ; AAPGGPVPRA ; GRWRRGAPAE ; DQDCGRLPDF ; IAKLTNNTHQ ; 150: HVFDDLSGSV ; SLSWVGDSTG ; VILVLTTFQV ; PLVIVSFGQS ; KLYRSEDYGK ; 200: NFKDITNLIN ; NTFIRTEFGM ; AIGPENSGKV ; ILTAEVSGGS ; RGGRVFRSSD ; 250: FAKNFVQTDL ; PFHPLTQMMY ; SPQNSDYLLA ; LSTENGLWVS ; KNFGEKWEEI ; 300: HKAVCLAKWG ; PNNIIFFTTH ; VNGSCKADLG ; ALELWRTSDL ; GKTFKTIGVK ; 350: IYSFGLGGRF ; LFASVMADKD ; TTRRIHVSTD ; QGDTWSMAQL ; PSVGQEQFYS ; 400: ILAANDDMVF ; MHVDEPGDTG ; FGTIFTSDDR ; GIVYSKSLDR ; HLYTTTGGET ; 450: DFTNVTSLRG ; VYITSTLSED ; NSIQSMITFD ; QGGRWEHLQK ; PENSKCDATA ; 500: KNKNECSLHI ; HASYSISQKL ; NVPMAPLSEP ; NAVGIVIAHG ; SVGDAISVMV ; 550: PDVYISDDGG ; YSWAKMLEGP ; HYYTILDSGG ; IIVAIEHSNR ; PINVIKFSTD ; 600: EGQCWQSYVF ; SQEPVYFTGL ; ASEPGARSMN ; ISIWGFTESF ; LTRQWVSYTI ; 650: DFKDILERNC ; EENDYTTWLA ; HSTDPGDYKD ; GCILGYKEQF ; LRLRKSSVCQ ; 700: NGRDYVVAKQ ; PSICPCSLED ; FLCDFGYFRP ; ENASECVEQP ; ELKGHELEFC ; 750: LYGKEEHLTT ; NGYRKIPGDR ; CQGGMNPARE ; VKDLKKKCTS ; NFLNPKKQNS ; 800: KSSSVPIILA ; IVGLMLVTVV ; AGVLIVKKYV ; CGGRFLVHRY ; SVLQQHAEAD ; 825: GVEALDTASH ; AKSGYHDDSD ; EDLLE
Sequence Length	825
String	O54861
Sub Unit	Interacts with the cytosolic adapter proteins GGA1 and GGA2. Interacts with numerous ligands including the receptor-associated protein LRPAP1/RAP and GM2A, LPL, NTS, PSAP and SLC2A4. Forms a complex with NGFR which binds specifically to the precursor form of NGFB (proNGFB) (By similarity). Interacts with the precursor form of BDNF (proBDNF).

Uniprot	O54861
Gene Name	Sort1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:83576
Unigene	Rn.11286

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13810758	E9893r	96T	$796		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.