ELISA Kit for Rat Serine/threonine-protein kinase receptor R3

Mfr.No.	E1901r
Alternative Names	TGF-B superfamily receptor type I ; TSR-I ; Acvrlk1
Categories	Elisa
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta. May bind activin as well.
Specificity	Natural and recombinant Rat Serine/threonine-protein kinase receptor R3
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.156-10ng/mL
Entryname	ACVL1_RAT
Method Type	Sandwich
Platform	PF01064
Protein Name	Serine/threonine-protein kinase receptor R3
Sensitivity	0.088ng/mL
Sequence	50: MTLGIFRRVF ; LMLSVALGLT ; KGDLVKPSRG ; QLVNCTCENP ; HCKRPICQGA ; 100: WCTVVLVREQ ; GRHPQVYRGC ; GSLNQELCLG ; RPTEFVNHHC ; CYRSFCNHNV ; 150: SLMLEATQTP ; SEEPEVDAHL ; PLILGPVLAL ; LVLVALGTLG ; LWRVRRRQEK ; 200: QRGLHSDLGE ; SSLILKASEQ ; GDSMLGDFLV ; SDCTTGSGSG ; LPFLVQRTVA ; 250: RQVALVECVG ; KGRYGEVWRG ; SWHGESVAVK ; IFSSRDEQSW ; FRETEIYNTV ; 300: LLRHDNILGF ; IASDMTSRNS ; STQLWLITHY ; HEHGSLYDFL ; QRQTLEPQLA ; 350: LRLAVSAACG ; LAHLHVEIFG ; TQGKPAIAHR ; DLKSRNVLVK ; SNLQCCIADL ; 400: GLAVMHSQSS ; DYLDIGNNPR ; VGTKRYMAPE ; VLDEQIRTDC ; FESYKWTDIW ; 450: AFGLVLWEIA ; RRTIINGIVE ; DYRPPFYDMV ; PNDPSFEDMK ; KVVCVDQQTP ; 500: TIPNRLAADP ; VLSGLAQMMR ; ECWYPNPSAR ; LTALRIKKTL ; QKLSQNPEKP ; 504: KVIH
Sequence Length	504
String	P80203

Reference	1. "Developmental expression of four novel serine/threonine kinase receptors homologous to the activin/transforming growth factor-beta type II receptor family." He W.-W., Gustafson M.L., Hirobe S., Donahoe P.K. Dev. Dyn.196:133-142(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley. tissue: Urogenital ridge. 2. "Type I receptor serine-threonine kinase preferentially expressed in pulmonary blood vessels." Panchenko M.P., Williams M.C., Brody J.S., Yu Q. Am. J. Physiol.270:L547-L558(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY strain: Sprague-Dawley. tissue: Lung. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Lung.

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