Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
Specificity
Natural and recombinant Rat Selenoprotein P
Subcellular Location
Secreted
Detection Range
0.156-10ng/mL
Entryname
SEPP1_RAT
Linearity
The linearity of the kit was assayed by testing samples spiked with appropriate concentration of SEPP1 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.
Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Intra-Assay CV: ≤4.9%
Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.
Inter-Assay CV: ≤7.1%
Protein Name
Selenoprotein P
Recovery
Recovery was determined by spiking various levels of SEPP1 into serum and plasma .
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 20-41; 267-287 AND 316-327
"Mass spectrometric characterization of full-length rat selenoprotein P and three isoforms shortened at the C-terminus. Evidence that three UGA codons in the mRNA open reading frame have alternative functions of specifying selenocysteine insertion or translation termination." Ma S., Hill K.E., Caprioli R.M., Burk R.F. J. Biol. Chem.277:12749-12754(2002) [PubMed] [Europe PMC] [Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF ISOFORMS
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-83; ASN-174; ASN-188 AND THR-365;ABSENCE OF GLYCOSYLATION AT ASN-370 AND ASN-375;DISULFIDE BONDS