ELISA Kit for Rat Secreted frizzled-related protein 1

Mfr.No.	E1165r
Categories	Elisa
Function	Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase. In kidney development, inhibits tubule formation and bud growth in metanephroi. Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
Specificity	Natural and recombinant Rat Secreted frizzled-related protein 1
Subcellular Location	Secreted Cell membrane or extracellular matrix-associated. Released by heparin-binding.
Detection Range	0.625-40ng/mL
Entryname	SFRP1_RAT
Method Type	Sandwich
Platform	PF01392
Protein Name	Secreted frizzled-related protein 1
Sensitivity	0.328ng/mL
Sequence	50: VRDSCEPVMQ ; FFGFYWPEML ; KCDKFPEGDV ; CIAMTPPNAT ; EASKPQGTTV ; 100: CPPCDNELKS ; EAIIEHLCAS ; EFALRMKIKE ; VKKENGDKKI ; VPKKKKPLKL ; 150: GPIKKKELKR ; LVLFLKNGAD ; CPCHQLDNLS ; HNFLIMGRKV ; KSQYLLTAIH ; 158: KWDKKNKE
Sequence Length	158
String	Q9R168
Sub Unit	Interacts with WNT4. Interects with WNT1, WNT2, WNT8 and FRZD6.

Reference	1. "Secreted Frizzled-related proteins can regulate metanephric development." Yoshino K., Rubin J.S., Higinbotham K.G., Uren A., Anest V., Plisov S.Y., Perantoni A.O. Mech. Dev.102:45-55(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DEVELOPMENTAL STAGE strain: Fischer.

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHE13809668	E1165r	96T	$796		Add to Cart