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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat RuvB-like 1

SKU : BHE13809991

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3290r
Alternative Names	49 kDa TATA box-binding protein-interacting protein ; 49 kDa TBP-interacting protein ; DNA helicase p50 ; Pontin 52 ; TIP49a ; Tip49 ; Tip49a
Categories	Elisa
Function	May be able to bind plasminogen at cell surface and enhance plasminogen activation.
Specificity	Natural and recombinant Rat RuvB-like 1
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	RUVB1_RAT
Method Type	Sandwich
Platform	PF06068
Protein Name	RuvB-like 1
Sensitivity	0.156ng/mL
Sequence	50: MKIEEVKSTT ; KTQRIASHSH ; VKGLGLDESG ; LAKQAASGLV ; GQENAREACG ; 100: VIVELIKSKK ; MAGRAVLLAG ; PPGTGKTALA ; LAIAQELGSK ; VPFCPMVGSE ; 150: VYSTEIKKTE ; VLMENFRRAI ; GLRIKETKEV ; YEGEVTELTP ; CETENPMGGY ; 200: GKTISHVIIG ; LKTAKGTKQL ; KLDPSIFESL ; QKERVEAGDV ; IYIEANSGAV ; 250: KRQGRCDTYA ; TEFDLEAEEY ; VPLPKGDVHK ; KKEIIQDVTL ; HDLDVANARP ; 300: QGGQDILSMM ; GQLMKPKKTE ; ITDKLRGEIN ; KVVNKYIDQG ; VAELVPGVLF ; 350: VDEVHMLDIE ; CFTYLHRALE ; SSIAPIVIFA ; SNRGNCVIRG ; TEDITSPHGI ; 400: PLDLLDRVMI ; IRTMLYTPQE ; MKQIIKIRAQ ; TEGINISEEA ; LNHLGEIGTK ; 450: TTLRYSVQLL ; TPANLLAKIN ; GKDSIEKEHV ; EEISELFYDA ; KSSAKILADQ ; 456: QDKYMK
Sequence Length	456
String	P60123
Sub Unit	Forms homohexameric rings. Can form a dodecamer with RUVBL2 made of two stacked hexameric rings; however, even though RUVBL1 and RUVBL2 are present in equimolar ratio, the oligomeric status of each hexamer is not known. Oligomerization may regulate binding to nucleic acids and conversely, binding to nucleic acids may affect the dodecameric assembly. Interacts with the transcriptional activation domain of MYC. Component of the RNA polymerase II holoenzyme complex. May also act to bridge the LEF1/TCF1-CTNNB1 complex and TBP. Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6. The NuA4 complex interacts with MYC and the adenovirus E1A protein. RUVBL1 interacts with EP400. Component of a NuA4-related complex which contains EP400, TRRAP/PAF400, SRCAP, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, actin, ACTL6A/BAF53A, VPS72 and YEATS4/GAS41. Component of the BAF53 complex, at least composed of ACTL6A/BAF53A, RUVBL1/TIP49, SMARCA2/BRM, and TRRAP/PAF400. Component of some MLL1/MLL complex, at least composed of the core components MLL, ASH2L, HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components C17orf49, CHD8, E2F6, HSP70, IN80C, KIAA1267, LAS1L, MAX, MCRS1, MGA, MYST1/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4, TAF6, TAF7, TAF9 and TEX10. Associates with alpha and gamma tubulins, particularly during metaphase and early anaphase. Interacts with NPAT. Component of the chromatin-remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80. Interacts with IGHMBP2. Interacts with OFD1.

Uniprot	P60123
Gene Name	Ruvbl1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:65137
Unigene	Rn.86410

Reference	1. "Molecular cloning of a rat 49-kDa TBP-interacting protein (TIP49) that is highly homologous to the bacterial RuvB." Kanemaki M., Makino Y., Yoshida T., Kishimoto T., Koga A., Yamamoto K., Yamamoto M., Moncollin V., Egly J.-M., Muramatsu M., Tamura T.-A. Biochem. Biophys. Res. Commun.235:64-68(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 1-11; 34-45; 129-138 AND 446-452 tissue: Liver. 2. "Molecular shape and ATP binding activity of rat p50, a putative mammalian homologue of RuvB DNA helicase." Kikuchi N., Gohshi T., Kawahire S., Tachibana T., Yoneda Y., Isobe T., Lim C.R., Kohno K., Ichimura T., Omata S., Horigome T. J. Biochem.125:487-494(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 1-9; 91-102; 377-398 AND 441 strain: Fischer 344. tissue: Liver. 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Heart. tissue: Ovary. 4. "A rat RuvB-like protein, TIP49a, is a germ cell-enriched novel DNA helicase." Makino Y., Kanemaki M., Kurokawa Y., Koji T., Tamura T.-A. J. Biol. Chem.274:15329-15335(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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BHE13809991	E3290r	96T	$796		Add to Cart

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