ELISA Kit for Rat Ras-related GTP-binding protein B

Mfr.No.	E3278r
Categories	Elisa
Function	Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. Involved in the RCC1/Ran-GTPase pathway.
Specificity	Natural and recombinant Rat Ras-related GTP-binding protein B
Subcellular Location	Cytoplasm Lysosome
Entryname	RRAGB_RAT
Platform	PF04670
Protein Name	Ras-related GTP-binding protein B
Sequence	50: MEESDSEKKT ; EKENVGPKVE ; PPLGEPEGSL ; GWAMPNAAMK ; KKVLLMGKSG ; 100: SGKTSMRSII ; FANYIARDTR ; RLGATILDRI ; HSLQINSSLS ; TYSLVDSVGN ; 150: TKTFDVEHSH ; VRFLGNLVLN ; LWDCGGQDTF ; MENYFTSQRD ; NIFRNVEVLI ; 200: YVFDVESREL ; EKDMHYYQSC ; LEAILQNSPE ; AKIFCLVHKM ; DLVQEDQRDL ; 250: IFKEREEDLR ; RLSRPLECSC ; FRTSIWDETL ; YKAWSSIVYQ ; LIPNVQQLEM ; 300: NLRNFAEIIE ; ADEVLLFERA ; TFLVISHYQC ; KEQRDAHRFE ; KISNIIKQFK ; 350: LSCSKLAASF ; QSMEVRNSNF ; AAFIDIFTSN ; TYVMVVMSDP ; SIPSAATLIN ; 374: IRNARKHFEK ; LERVDGPKQC ; LLMR
Sequence Length	374
String	Q63487
Sub Unit	The short isoform binds GTP. Interacts with RRAGC and RRAGD.

Reference	1. "Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagBl) with remote similarity to the Ras-related GTPases." Schuermann A., Brauers A., Massmann S., Becker W., Joost H.-G. J. Biol. Chem.270:28982-28988(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);ALTERNATIVE SPLICING;TISSUE SPECIFICITY;GTP-BINDING strain: Sprague-Dawley. tissue: Brain. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1) tissue: Brain. tissue: Lung.

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BHE13809581	E3278r	96T	$796		Add to Cart