Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Specificity
Natural and recombinant Rat [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;FUNCTION;CATALYTIC ACTIVITY;ENZYME REGULATION;SUBUNIT;TISSUE SPECIFICITY
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;ENZYME REGULATION;TISSUE SPECIFICITY
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DLAT;ENZYME REGULATION;CATALYTIC ACTIVITY
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;FUNCTION;INTERACTION WITH PDK2;SUBUNIT