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ELISA Kit for Rat Protein unc-13 homolog C

SKU : BHE13811483

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2019r
Alternative Names	Munc13-3 ; Unc13h3
Categories	Elisa
Function	Probably plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Probably is involved in neurotransmitter release.
Specificity	Natural and recombinant Rat Protein unc-13 homolog C
Subcellular Location	Cytoplasm Membrane Peripheral membrane protein Cell junction synapse presynaptic cell membrane Peripheral membrane protein Localized to presynaptic structures.
Detection Range	15.6-1000pg/mL
Entryname	UN13C_RAT
Method Type	Sandwich
Platform	PF00130
Protein Name	Protein unc-13 homolog C
Sensitivity	7.3pg/mL
Sequence	50: MVASLFKSLI ; LAYIHKLCKG ; MFTKKLGNTT ; KKKENRQQNK ; DQDFPTAGHT ; 100: KPPKLSNALK ; STVKKIAKCS ; STRNFSVEDE ; EGHKDFSLSP ; TFSYRVAIAN ; 150: GLQTAVTNSD ; EDLLQELSSI ; ESSYSESFNE ; LRSSTENQVQ ; STHTMPVRRN ; 200: RKSSSSLAPS ; EGSSDGERTL ; HTLKLGALRK ; LRKWKKSQEC ; VSSDSELSTV ; 250: KKTWGIRSKS ; LDRTARNPKT ; NVLEPGFSSS ; GCISQTHDVM ; EMIFKELQGI ; 300: SQIETELSEL ; RGHVNALKYS ; IDEISSSVEV ; VQSEIEQLRT ; GFVQARRETR ; 350: DIHDYIKHLG ; HMGSKVSLRF ; LNVPEERHEY ; VESVVYQILV ; DKMGFSDVPN ; 400: AIKIEFAQRI ; GQQRDCPNAK ; PRPILVYFET ; PQQRDSVLKK ; SYKLKGTGIA ; 450: ISTDILTYDI ; RERKEKGVLP ; SSQTYESMDM ; KLSTPEPKAK ; KNAWLSPNDS ; 500: DRELESDLSR ; SSYADSPAKG ; SSSKSSSKSH ; SARSKNKAAN ; SRTSQKSDYN ; 550: KRPSKPPASE ; KPTPHYVEAT ; PLWHSQSDFF ; TPKLSRSESD ; FSKLCQSYSE ; 600: DFSESQFFCR ; TNGSSLLSSS ; DRELWQRKQE ; GMTALYHSPQ ; DQGLDGNIPT ; 650: VPGQGEIENT ; ETVDSGMSNS ; VVCASGDRSN ; YSGSQLSLHE ; DLSPWKEWNQ ; 700: AGHGTDGLDS ; STQEPFDYDT ; NSLSDQQLDM ; SSKDLDDLGK ; CHSDLQDDSE ; 750: SYDLTQDDNS ; SPCPGLDNEP ; QGQWVGQYDS ; YQKTNSNDLY ; PNQSHPSMMY ; 800: RSQSELQSDD ; SEAAQPKSWH ; SRLSIDLSDK ; TFKFPKFGST ; LQRAKSALEV ; 850: VWNKSTQSLS ; GCEDSGSSLM ; GRFRTLSQST ; ANESSTTLDS ; DIYTEPYYYK ; 900: AEEEEDYCEP ; VADSETDYVE ; VMEQVLAKLE ; NRTSVTEVDE ; HIKEYDHPSY ; 950: ETPYETPQDE ; GYDGQADDII ; SEGELETLNE ; PAVEMELVED ; ESQNLPVEPP ; 1000: EVMKPKRIRP ; SFKEAALRAY ; KKQMAELEEK ; ILAGDSSSVD ; EKARIVSGND ; 1050: LDASKFSALQ ; VFGGAGRGLY ; GIDSMPDLRR ; KKTLPIVRDV ; AMTLAARKSG ; 1100: LSLAMVIRTS ; LNNEELKMHV ; FRKTLQALIY ; PISSTTPHNF ; EVWTATTPTY ; 1150: CYECEGLLWG ; IARQGMKCLE ; CGVKCHEKCQ ; DLLNADCLQR ; AAEKSSKHGA ; 1200: EDKTQTIITA ; MKERMKIRER ; NRPEVFEVIQ ; EMFQISKEDF ; VQYTKAAKQS ; 1250: VLDGTSKWSA ; KITITVVSAQ ; GLQAKDKTGS ; SDPYVTVQVG ; KNKRRTKTIF ; 1300: GNLNPVWDEK ; FYFECHNSTD ; RIKVRVWDED ; DDIKSRVKQH ; FKKESDDFLG ; 1350: QTIVEVRTLS ; GEMDVWYNLE ; KRTDKSAVSG ; AIRLKINVEI ; KGEEKVAPYH ; 1400: IQYTCLHENL ; FHYLTEVKSN ; GSVKIPEVKG ; DEAWKVFFDD ; ASQEIVDEFA ; 1450: MRYGVESIYQ ; AMTHFSCLSS ; KYMCPGVPAV ; MSALLANINA ; FYAHTTVSTN ; 1500: VQVSASDRFA ; ATNFGREKFI ; KLLDQLHNSL ; RIDLSKYREN ; FPASNSERLQ ; 1550: DLKSTVDLLT ; SITFFRMKVL ; ELQSPPKASA ; VVKDCVRACL ; DSTYKYIFDN ; 1600: CHELYSQLID ; PSKKQDVPRE ; EQGPTTKNLD ; FWPQLITLMV ; TIIDEDKTAY ; 1650: TPVLNQFPQE ; LNMGKISAEI ; MWSLFALDMK ; YALEEHEKQR ; LCKSTDYMNL ; 1700: HFKVKWFYNE ; YVRELPAFKD ; AVPEYSLWFE ; PFVMQWLDEN ; EDVSMEFLHG ; 1750: ALGRDKKDGF ; QQTSDHALFS ; CSVVDVFAQL ; NQSFEIIKKL ; ECPNPEALSH ; 1800: LMRRFAKTIN ; KVLVQYAAIV ; SSDFSSYCDK ; ETVPCILMNN ; IQQLRVQLEK ; 1850: MFESMGGKEL ; DPEASTILKE ; LQIKLNGVLD ; ALSVTYGESF ; QLVIEECIKQ ; 1900: MGAELNQMRA ; NGNSAANKNN ; AAMDAEIVLR ; PLMDFLDKIL ; SLSAKICEKT ; 1950: VLKRVLKELW ; KLVLNKIEKQ ; IVLPPLTDQT ; GPQMIFIAAK ; ELGQLSKLKE ; 2000: HMIRDDAKGL ; TPRQCAIMEV ; VLATIKQYFH ; AGGNGLKKNF ; LEKSPDLHSL ; 2050: RYALSLYTQT ; TDALIKKFIE ; TQGSQSRSSK ; DAVGQISVHV ; DVTTTPGTGE ; 2100: HKVTVKVIAI ; NDLNWQTTTM ; FRPFVEVCML ; GPSLGDKKRK ; QGTKTKSNTW ; 2150: SPKYNETFQF ; ILGNENRPGA ; YELHLSVKDY ; CFAREDRIIG ; MTVIQLQNIA ; 2200: EKGSYGAWYP ; LLKNLSMDET ; GLTILRILSQ ; RTSDDVAKEF ; VRLKSETRSI ; 2204: DESA
Sequence Length	2204
String	Q62770
Sub Unit	Interacts with STX1A and/or STX1B1, VAMP2 and SNAP25.

Uniprot	Q62770
Gene Name	Unc13c
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:286931
Unigene	Rn.11278

Reference	1. Telemenakis I., Brose N., Suedhof T.C. Submitted (1996-10) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Brain. 2. "Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins." Brose N., Hofmann K., Hata Y., Suedhof T.C. J. Biol. Chem.270:25273-25280(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 942-1634;TISSUE SPECIFICITY tissue: Brain. 3. "Differential expression of two novel Munc13 proteins in rat brain." Augustin I., Betz A., Herrmann C., Jo T., Brose N. Biochem. J.337:363-371(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;INTERACTION WITH SYNTAXIN 1; VAMP2 AND SNAP25

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BHE13811483	E2019r	96T	$796		Add to Cart

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