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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Protein Spindly

SKU : BHE13810504

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15337r
Alternative Names	Coiled-coil domain-containing protein 99 ; Spindle apparatus coiled-coil domain-containing protein 1 ; Ccdc99
Categories	Elisa
Function	Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
Specificity	Natural and recombinant Rat Protein Spindly
Subcellular Location	Cytoplasm cytoskeleton centrosome Chromosome centromere kinetochore Nucleus Cytoplasm cytoskeleton spindle pole Localizes to the nucleus in interphase and to the kinetochore in early prometaphase. Relocalizes to the mitotic spindle pole before metaphase and is subsequently lost from the spindle poles after chromosome congression is completed. Removal of this protein from the kinetochore requires the dynein/dynactin complex.
Entryname	SPDLY_RAT
Protein Name	Protein Spindly
Sequence	50: MEADITNLRN ; KLKECEDERL ; KAAQYGLQLL ; ERQTELQSQL ; DKCHEEMMTT ; 100: AENYNQEKYA ; LQREVELKSR ; MLESLSCECE ; ALRQQQKAQL ; EQLEMQLHRS ; 150: HRQEVHGLRN ; KLENLKVELD ; EARLSEKQLK ; QKLDHQGELL ; SHKSEELRLL ; 200: SEQRALSSVS ; SELLSLQTEL ; TEAEGVKNAL ; REEVNELQCK ; QEQLECLNAS ; 250: LLHQVDRLKE ; EKEEREKEAV ; SYYNALEKAR ; VENQDLQVQL ; GHALQQAADP ; 300: NSKGNSLFAE ; VEDRRVAMER ; RLNLMKDKYQ ; SLKKQNAFTR ; DQMNKMKLQI ; 350: STLLRMRGSQ ; TEFEQQERLF ; AMLEQKNGEI ; KHLLGEINKL ; EKFKNLYENM ; 400: ESKSSTSDSA ; CALEDSTYYT ; DLLQLKLDKL ; NKENESTKGE ; LSIQRMKALF ; 450: ESQRTLDIER ; KLFANERHLQ ; LSESENLKLR ; AKLDELKLKY ; EPEERIEVPV ; 500: LKRRREVLPL ; NINTPEETAA ; ASATGEDVSR ; LPLERKEESC ; LDNLKDNTVQ ; 550: WKQPASLSPH ; KSLPLDTQPK ; KEKCVTLVAS ; PASTEVLHEQ ; SGNTPSSPRL ; 597: TEESRLPTKV ; KERKEATSKL ; EKGASKKSHT ; IMYVSSKSTP ; EMQCPQQ
Sequence Length	597
String	Q3KR99
Sub Unit	Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.

Uniprot	Q3KR99
Gene Name	Spdl1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:303037
Unigene	Rn.54949

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Testis.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810504	E15337r	96T	$796		Add to Cart

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