ELISA Kit for Rat Protein Mdm4

Mfr.No.	E12870r
Alternative Names	Double minute 4 protein ; Mdm2-like p53-binding protein ; Protein Mdmx ; p53-binding protein Mdm4 ; Mdmx
Categories	Elisa
Function	Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Specificity	Natural and recombinant Rat Protein Mdm4
Subcellular Location	Nucleus
Entryname	MDM4_RAT
Platform	PF02201
Protein Name	Protein Mdm4
Sequence	50: MTSHSTSAQC ; SASDSACRIS ; SEQINQQVRP ; KLQLLKILQA ; AGAQGEVFTM ; 100: KEVMHYLGQY ; IMVKQLYDQQ ; EQHLVYCGGD ; LLGDLLGCQS ; FSVKDPSPLY ; 150: DMLRKNLVTS ; ASVNTDAAQT ; LALAQDHTMD ; IPSQDRLKHG ; ATECSNPRKR ; 200: TEEDDTHTLP ; TSRRKCRDSR ; ADEDLIEHLS ; QDETSRLDLD ; FEEWDVAGLP ; 250: WWFLGNLRNN ; YIPRSNGSTD ; LQTNQDIGTA ; IVSDTTDDLW ; FLNETVSEQL ; 300: GVGVKVEAAN ; CEQPSEVGRT ; RDKKMVEGGK ; DDDLEDSKSL ; SDDTDVEVTS ; 350: EDEWQCTECK ; KFNSPSKRYC ; FRCWALRKDW ; YSDCSKLTHS ; LSTSNITAIP ; 400: EKKDNEGIDV ; PDCRRTISAP ; VVRPKDGYLK ; EEKPRFDPCN ; SVEFLDLAHG ; 450: SESQEIISST ; REQTDIFSEQ ; KTETESMEDF ; QNVLKPCSLC ; EKRPRDGNII ; 490: HGKTSHLTTC ; FHCARRLKKS ; GASCPACKKE ; IQLVIKVFIA ;
Sequence Length	490
String	Q5XIN1
Sub Unit	Interacts with MDM2, TP53, TP73 and USP2. Found in a trimeric complex with UPB2, MDM2 and MDM4.

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Testis.

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BHE13806938	E12870r	96T	$796		Add to Cart