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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Protein LYRIC

SKU : BHE13806242

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1442r
Alternative Names	Lysine-rich CEACAM1 co-isolated protein ; Metadherin ; Metastasis adhesion protein ; Lyric
Categories	Elisa
Function	Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
Specificity	Natural and recombinant Rat Protein LYRIC
Subcellular Location	Endoplasmic reticulum membrane Single-pass membrane protein Nucleus membrane Single-pass membrane protein Cell junction tight junction Nucleus nucleolus Cytoplasm perinuclear region In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes. A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain. TNF-alpha causes translocation from the cytoplasm to the nucleus.
Detection Range	78-5000pg/mL
Entryname	LYRIC_RAT
Method Type	Sandwich
Protein Name	Protein LYRIC
Sensitivity	39.06pg/mL
Sequence	50: MAARSWQDEL ; AQQAEEGSAR ; LRELLSVGLG ; FLRTELGLDL ; GLEPKRYPSW ; 100: VILVGTGALG ; LLLLFLLGYG ; WAAACAGARK ; KRRSPPRKRE ; EVTPPTPAPE ; 150: DPAQLKNLRS ; EEQKKKNRKK ; LPEKPKPNGR ; TVEIPEDEVV ; RTPRSITAKQ ; 200: PPETDKKNEK ; SKKNKKKSKS ; DAKAVQNSSR ; HDGKEVDEGA ; WETKISHREK ; 250: RQQRKRDKVL ; TDSGSLDSTI ; PGIENTITVT ; TEQLTTASFP ; VGSKKNKGDS ; 300: HLNVQVSNFK ; SGKGDSTLQV ; SSGLNENITV ; NGGGWSEKSV ; KLSSQLSAGE ; 350: EKWNSVPPAS ; AGKRKTEQSA ; WTQDPGDTNA ; NGKDWGRNWS ; DRSIFSGIGS ; 400: TAEPVSQSTT ; SDYQWDGSRN ; QPHIDDEWSG ; LNGLSSADPS ; SDWNAPAEEW ; 450: GNWVDEDRAS ; LLKSQEPISN ; DQKDSDDDKE ; KGEGALPTGK ; SKKKKKKKKK ; 500: QGEDNSITQD ; TEDLEKDTRE ; ELPVNTSKAR ; PKQEKACSLK ; TMSTSDPVEV ; 550: LIKNSQPIKT ; LPPAISAEPS ; VTLSKGDSDK ; SSSQVPPMLQ ; DTDKPKSNAK ; 581: QNSVPPSQTK ; SETNWESPKQ ; IKKKKKARRE ; T
Sequence Length	581
String	Q9Z1W6
Sub Unit	Interacts with BCIPP, CREBBP/CBP and RELA/p65.

Uniprot	Q9Z1W6
Gene Name	Mtdh
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:170910
Unigene	Rn.6864

Reference	1. "Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells." Britt D.E., Yang D.-F., Yang D.-Q., Flanagan D.L., Callanan H., Lim Y.-P., Lin S.-H., Hixson D.C. Exp. Cell Res.300:134-148(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);ALTERNATIVE SPLICING;TISSUE SPECIFICITY;SUBCELLULAR LOCATION strain: Fischer. tissue: Bile duct.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806242	E1442r	96T	$796		Add to Cart

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