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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Polycomb group RING finger protein 6

SKU : BHE13808711

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E12055r
Alternative Names	RING finger protein 134 ; Rnf134
Categories	Elisa
Function	Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Specificity	Natural and recombinant Rat Polycomb group RING finger protein 6
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	PCGF6_RAT
Method Type	Sandwich
Platform	PF00097
Protein Name	Polycomb group RING finger protein 6
Sensitivity	0.096ng/mL
Sequence	50: MEEAETDATE ; NKRASEAKRA ; SAMLPPPPPP ; ISPPALIPAP ; AAGEEGPASL ; 100: AQAGAPGCSR ; SRPPELEPER ; SLGRLRGRFE ; DYDEELEEDE ; EMEEEEEEEE ; 150: EMSHFSLRLE ; SGRADSEDEE ; ERLINLVELT ; PYILCSICKG ; YLIDATTITE ; 200: CLHTFCKSCI ; VRHFYYSNRC ; PKCNIVVHQT ; QPLYNIRLDR ; QLQDIVYKLV ; 250: VNLEEREKKQ ; MHDFYKERGL ; EVPKPAVPQP ; VPASKGRTKK ; ALESVFRIPP ; 300: ELDVSLLLEF ; IGANEDTGHF ; KPLEKKFVRV ; SGEATIGHVE ; KFLRRKMGLD ; 350: PACQVDIICG ; DHLLERYQTL ; REIRRAIGDT ; AMQDGLLVLH ; YGLVVSPLKI ; 351: T
Sequence Length	351
Sub Unit	Component of a PRC1-like complex. Interacts with BMI1/PCGF4, RING1 and RNF2. Interacts with KDM5D. Interacts with CBX4, CBX6, CBX7 and CBX8.

Uniprot	Q5XI70
Gene Name	Pcgf6
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:309457
Unigene	Rn.16897

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Testis.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808711	E12055r	96T	$796		Add to Cart

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