ELISA Kit for Rat Platelet-derived growth factor subunit B

Mfr.No.	E0633r
Alternative Names	PDGF-2 ; Platelet-derived growth factor B chain ; Platelet-derived growth factor beta polypeptide
Categories	Elisa
Function	Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. May have a chemotactic role in intimal thickening.
Specificity	Natural and recombinant Rat Platelet-derived growth factor subunit B
Subcellular Location	Secreted
Detection Range	31.2-2000pg/mL
Entryname	PDGFB_RAT
Method Type	Sandwich
Platform	PF00341
Protein Name	Platelet-derived growth factor subunit B
Sensitivity	15.63pg/mL
Sequence	50: LPLCCYLRLV ; SAEGDPIPEE ; LYEMLSDHSI ; RSFDDLQRLL ; HRDSVDEDGA ; 100: ELDLNMTRAH ; SGVESESSSR ; GRRSLGSLAA ; AEPAVIAECK ; TRTEVFQISR ; 150: NLIDRTNANF ; LVWPPCVEVQ ; RCSGCCNNRN ; VQCRASQVQM ; RPVQVRKIEI ; 200: VRKKPVFKKA ; TVTLEDHLAC ; KCETVVTPRP ; VTRSPGTSRE ; HRAKTPQTRV ; 225: TVRTVRIRRP ; PKGKHRKFKH ; THDKK
Sequence Length	225
String	Q05028
Sub Unit	Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with XLKD1.

Reference	1. "Conservation in sequence and affinity of human and rodent PDGF ligands and receptors." Herren B., Weyer K.A., Rouge M., Loetscher P., Pech M. Biochim. Biophys. Acta1173:294-302(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "A subpopulation of smooth muscle cells in injured rat arteries expresses platelet-derived growth factor-B chain mRNA." Lindner V., Giachelli C.M., Schwartz S.M., Reidy M.A. Circ. Res.76:951-957(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 74-182 strain: Sprague-Dawley. tissue: Smooth muscle.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808786	E0633r	96T	$796		Add to Cart