Homodimer. Component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Interacts directly with PER1, PER2, CRY1, CRY2, and TIMELESS. Interaction with CSNK1D or CSKN1E promotes nuclear location of PER proteins.
"Cloning and circadian expression of rat period3 gene." Suzuki S., Oishi K., Sakamoto K., Ishida N. Submitted (2002-09) to the EMBL/GenBank/DDBJ databases
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