After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
Specificity
Natural and recombinant Rat Neuronal acetylcholine receptor subunit alpha-7
Subcellular Location
Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RIC3;MUTAGENESIS OF LEU-433; LYS-435; VAL-440; ASN-445; ARG-446; PHE-447 AND ARG-448