Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
Specificity
Natural and recombinant Rat NAD(P)H-hydrate epimerase
Subcellular Location
Mitochondrion Secreted In sperm, secretion gradually increases during capacitation.