The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Specificity
Natural and recombinant Rat Muscarinic acetylcholine receptor M3
Subcellular Location
Cell membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Basolateral cell membrane Multi-pass membrane protein
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF TYR-148; THR-231; THR-234; TYR-506; TYR-529 AND TYR-533;FUNCTION;SUBCELLULAR LOCATION
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF THR-234 AND TYR-506;FUNCTION;SUBCELLULAR LOCATION
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.40 ANGSTROMS) OF 57-589 IN COMPLEX WITH THE INVERSE AGONIST TIOTROPIUM;FUNCTION;SUBCELLULAR LOCATION;TOPOLOGY;DISULFIDE BOND
Reviews of ELISA Kit for Rat Muscarinic acetylcholine receptor M3