ELISA Kit for Rat Microphthalmia-associated transcription factor

Mfr.No.	E0547r
Categories	Elisa
Function	Transcription factor for tyrosinase and tyrosinase-related protein 1. Binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in the tyrosinase promoter. Plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Specificity	Natural and recombinant Rat Microphthalmia-associated transcription factor
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	MITF_RAT
Method Type	Sandwich
Platform	PF00010
Protein Name	Microphthalmia-associated transcription factor
Sensitivity	0.156ng/mL
Sequence	50: LTACIFPTES ; EARALAKERQ ; KKDNHNLIER ; RRRFNINDRI ; KELGTLIPKS ; 100: NDPDMRWNKG ; TILKASVDYI ; RKLQREQQRA ; KDLENRQKKL ; EHANRHLLLR ; 110: VQELEMQARA ;
Sequence Length	110
String	O88368
Sub Unit	Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA in the form of homodimer or heterodimer with either TFE3, TFEB or TFEC. Interacts with KARS.

Reference	1. "Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3." Weilbaecher K.N., Hershey C.L., Takemoto C.M., Horstmann M.A., Hemesath T.J., Tashjian A.H., Fisher D.E. J. Exp. Med.187:775-785(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806523	E0547r	96T	$796		Add to Cart