Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses oleate, arachidonate, eicosapentaenoate and docosahexaenoate as substrates.
Specificity
Natural and recombinant Rat Long-chain-fatty-acid--CoA ligase 1
Subcellular Location
Mitochondrion outer membrane Single-pass type III membrane protein Peroxisome membrane Single-pass type III membrane protein Microsome membrane Single-pass type III membrane protein Endoplasmic reticulum membrane Single-pass type III membrane protein
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-19; 82-91 AND 628-641;ACETYLATION AT MET-1 AND LYS-633;NITRATION AT TYR-9 AND TYR-86;PHOSPHORYLATION AT TYR-85;IDENTIFICATION BY MASS SPECTROMETRY