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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Leukosialin

SKU : BHE13806652

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1778r
Alternative Names	Leukocyte sialoglycoprotein ; Sialophorin ; W3/13 antigen ; CD43
Categories	Elisa
Function	One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
Specificity	Natural and recombinant Rat Leukosialin
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.312-20ng/mL
Entryname	LEUK_RAT
Method Type	Sandwich
Protein Name	Leukosialin
Sensitivity	0.162ng/mL
Sequence	50: WAQVVSQENL ; PNTMTMLPFT ; PNSESPSTSE ; ALSTYSSIAT ; VPVTEDPKES ; 100: ISPWGQTTAP ; ASSIPLGTPE ; LSSFFFTSAG ; ASGNTPVPEL ; TTSQEVSTEA ; 150: SLVLFPKSSG ; VASDPPVTIT ; NPATSSAVAS ; TSLETFKGTS ; APPVTVTSST ; 200: MTSGPFVATT ; VSSETSGPPV ; TMATGSLGPS ; KETHGLSATI ; ATSSGESSSV ; 250: AGGTPVFSTK ; ISTTSTPNPI ; TTVPPRPGSS ; GMLLVSMLIA ; LTVVLVLVAL ; 300: LLLWRQRQKR ; RTGALTLSRG ; GKRNGTVDAW ; AGPARVPDEE ; ATTASGSGGN ; 350: KSSGAPETDG ; SGQRPTLTTF ; FSRRKSRQGS ; VALEELKPGT ; GPNLKGEEEP ; 378: LVGSEDEAVE ; TPTSDGPQAK ; DGAAPQSL
Sequence Length	378
String	P13838
Sub Unit	Interacts with HIPK2 via the cytoplasmic domain. Interacts with RDX.

Uniprot	P13838
Gene Name	Spn
Immunogen Species	Rattus norvegicus (Rat)
Unigene	Rn.11144

Reference	1. "The sequence of rat leukosialin (W3/13 antigen) reveals a molecule with O-linked glycosylation of one third of its extracellular amino acids." Killeen N., Barclay A.N., Willis A.C., Williams A.F. EMBO J.6:4029-4034(1987) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Thymocyte. 2. "CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor sialoadhesin (Siglec-1)." van den Berg T.K., Nath D., Ziltener H.J., Vestweber D., Fukuda M., van Die I., Crocker P.R. J. Immunol.166:3637-3640(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SN

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806652	E1778r	96T	$796		Add to Cart

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