ELISA Kit for Rat Lamina-associated polypeptide 2, isoform beta

Mfr.No.	E1250r
Alternative Names	Thymopoietin isoform beta ; TP beta ; Lap2
Categories	Elisa
Function	Binds directly to lamin B1 and chromosomes in a mitotic phosphorylation-regulated manner. May play an important role in nuclear envelope reassembly at the end of mitosis and/or anchoring of the nuclear lamina and interphase chromosomes to the nuclear envelope.
Specificity	Natural and recombinant Rat Lamina-associated polypeptide 2, isoform beta
Subcellular Location	Nucleus inner membrane Single-pass type II membrane protein Chromosome Tightly associated with the nuclear lamina.
Detection Range	0.78-50ng/mL
Entryname	LAP2_RAT
Method Type	Competitive
Platform	PF03020
Protein Name	Lamina-associated polypeptide 2, isoform beta
Sensitivity	0.4ng/mL
Sequence	50: MPEFLEDPSV ; LTKDKLKSEL ; VANNVTLPAG ; EQRKDVYVQL ; YLQHLTARNR ; 100: PPLAAGANSK ; GPPDFSSDEE ; REPTPVLGSG ; ASVGRGRGAV ; GRKATKKTDK ; 150: PRPEDKDDLD ; VTELSNEELL ; EQLVRYGVNP ; GPIVGTTRKL ; YEKKLLKLRE ; 200: QGAESRSSTP ; LPTVSSSAEN ; TRQNGSNDSD ; RYSDNDEDSK ; IELKLEKREP ; 250: LKGRAKTPVT ; LKQRRIEHNQ ; SYSEAGVTET ; EWTSGSSKGG ; PLQALTREST ; 300: RGSRRTPRRR ; VEPSQHFRVD ; GAVISESTPI ; AETIKASSND ; SLVANRLTGN ; 350: FKHASSILPI ; TEFSDITRRT ; PKKPLTRAEV ; GEKTEERRVE ; RDILKEMFPY ; 400: EASTPTGISA ; SCRRPIKGAA ; GRPLELSDFR ; MEESFSSKYV ; PKYVPLADVK ; 450: SEKTKKGRSV ; PMWIKMLLFA ; LVAGFLFLVY ; QAMETNQGNP ; FTNFLQDTKI ; 452: SN
Sequence Length	452
String	Q62733
Sub Unit	Interacts with LMNB1, LMNB2, BANF1, AKAP8L, GMCL and chromosomes.

Reference	1. "Cloning of a cDNA for lamina-associated polypeptide 2 (LAP2) and identification of regions that specify targeting to the nuclear envelope." Furukawa K., Pante N., Aebi U., Gerace L. EMBO J.14:1626-1636(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 158-172; 270-284 AND 347-361 tissue: Liver.

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