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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Keratin, type I cytoskeletal 17

SKU : BHE13806623

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1822r
Alternative Names	Cytokeratin-17 ; CK-17 ; Keratin-17 ; K17 ; Type I keratin Ka17 ; Ka17
Categories	Elisa
Function	May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
Specificity	Natural and recombinant Rat Keratin, type I cytoskeletal 17
Subcellular Location	Cytoplasm
Detection Range	78-5000pg/mL
Entryname	K1C17_RAT
Method Type	Sandwich
Platform	PF00038
Protein Name	Keratin, type I cytoskeletal 17
Sensitivity	36pg/mL
Sequence	50: MTTTIRQFTS ; SSSIKGSSGL ; GGGSSRTSCR ; LSGSLGAGSC ; RLGSASGLGS ; 100: ALGGNSYSSC ; YSFGTGSGYG ; GNFGGVDGLL ; AGGEKATMQN ; LNDRLASYLD ; 150: KVRALEEANT ; ELEVKIRDWY ; QKQAPGPARD ; YSAYYQTIED ; LKNKILVATV ; 200: DNASILLQID ; NARLAADDFR ; TKFETEQALR ; MSVEADINGL ; RRVLDELTLA ; 250: RADLEMQIEN ; LKEELAYLKK ; NHEEEMNALR ; GQVGGEINVE ; MDAAPGVDLS ; 300: RILSEMRDQY ; EKMAEKNRKD ; AEDWFFSKTE ; ELNREVATNS ; ELVQSGKSEI ; 350: SELRRTMQAL ; EIELQSQLSM ; KASLEGSLAE ; TENRYCVQLS ; QIQGLIGSVE ; 400: EQLAQLRCEM ; EQQNQEYKIL ; LDVKTRLEQE ; IATYRRLLEG ; EDAHLTQYKP ; 433: KEPVTTRQVR ; TIVEEVQDGK ; VISSREQVHQ ; TTR
Sequence Length	433
String	Q6IFU8
Sub Unit	Heterodimer of a type I and a type II keratin. KRT17 associates with KRT6 isomers. Interacts with TRADD and SFN.

Uniprot	Q6IFU8
Gene Name	Krt17
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:287702
Unigene	Rn.106755

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806623	E1822r	96T	$796		Add to Cart

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