JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Kelch-like ECH-associated protein 1

SKU : BHE13804871

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E2835r
Alternative Names	Cytosolic inhibitor of Nrf2 ; INrf2 ; Inrf2
Categories	Elisa
Function	Retains NFE2L2/NRF2 in the cytosol. Functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. May also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Specificity	Natural and recombinant Rat Kelch-like ECH-associated protein 1
Subcellular Location	Cytoplasm Nucleus Shuttles between cytoplasm and nucleus.
Detection Range	0.156-10ng/mL
Entryname	KEAP1_RAT
Method Type	Sandwich
Platform	PF07707
Protein Name	Kelch-like ECH-associated protein 1
Sensitivity	0.081ng/mL
Sequence	50: MQPEPKPSGA ; PRSSQFLPLW ; SKCPEGAGDA ; VMYASTECKA ; EVTPSQDGNR ; 100: TFSYTLEDHT ; KQAFGIMNEL ; RLSQQLCDVT ; LQVKYEDIPA ; AQFMAHKVVL ; 150: ASSSPVFKAM ; FTNGLREQGM ; EVVSIEGIHP ; KVMERLIEFA ; YTASISVGEK ; 200: CVLHVMNGAV ; MYQIDSVVRA ; CSDFLVQQLD ; PSNAIGIANF ; AEQIGCTELH ; 250: QRAREYIYMH ; FGEVAKQEEF ; FNLSHCQLAT ; LISRDDLNVR ; CESEVFHACI ; 300: DWVKYDCPQR ; RFYVQALLRA ; VRCHALTPRF ; LQTQLQKCEI ; LQADARCKDY ; 350: LVQIFQELTL ; HKPTQAVPCR ; APKVGRLIYT ; AGGYFRQSLS ; YLEAYNPSNG ; 400: SWLRLADLQV ; PRSGLAGCVV ; GGLLYAVGGR ; NNSPDGNTDS ; SALDCYNPMT ; 450: NQWSPCASLS ; VPRNRSGGGV ; IDGHIYAVGG ; SHGCIHHSSV ; ERYEPDRDEW ; 500: HLVAPMLTRR ; IGVGVAVLNR ; LLYAVGGFDG ; TNRLNSAECY ; YPERNEWRMI ; 550: TPMNTIRSGA ; GVCVLHSCIY ; AAGGYDGQDQ ; LNSVERYDVE ; TETWTFVASM ; 600: KHRRSALGIA ; VHQGRIYVLG ; GYDGHTFLDS ; VECYDPDTDT ; WSEVTRLTSG ; 624: RSGVGVAVTM ; EPCRKQIDQQ ; NCTC
Sequence Length	624
String	P57790
Sub Unit	Homodimer. Forms a ternary complex with NFE2L2 and PGAM5. Interacts with the N-terminal regulatory domain of NFE2L2/NRF2. Interacts with BPTF and PTMA. Interacts with CUL3. Part of a complex that contains KEAP1, CUL3 and RBX1.

Uniprot	P57790
Gene Name	Keap1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:117519
Unigene	Rn.23467

Reference	1. "Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene." Dhakshinamoorthy S., Jaiswal A.K. Oncogene20:3906-3917(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley.

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13804871	E2835r	96T	$796		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.