ELISA Kit for Rat High mobility group protein HMG-I/HMG-Y

Mfr.No.	E1478r
Alternative Names	High mobility group AT-hook protein 1 ; High mobility group protein A1
Categories	Elisa
Function	HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
Specificity	Natural and recombinant Rat High mobility group protein HMG-I/HMG-Y
Subcellular Location	Nucleus Chromosome
Detection Range	0.156-10ng/mL
Entryname	HMGA1_RAT
Method Type	Sandwich
Platform	PF02178
Protein Name	High mobility group protein HMG-I/HMG-Y
Sensitivity	0.089ng/mL
Sequence	50: MSESVSKSSQ ; PLASKQEKDG ; TEKRGRGRPR ; KQPSVSPGTA ; LVGSQKEPSE ; 100: VPTPKRPRGR ; PKGSKNKGTA ; KTRKVTTTPG ; RKPRGRPKKL ; EKEEEEGISQ ; 107: ESSEEEQ
Sequence Length	107
String	Q8K585
Sub Unit	Interacts with HIPK2.

Reference	1. "During apoptosis of tumor cells HMGA1a protein undergoes methylation: identification of the modification site by mass spectrometry." Sgarra R., Diana F., Bellarosa C., Dekleva V., Rustighi A., Toller M., Manfioletti G., Giancotti V. Biochemistry42:3575-3585(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS HMG-I AND HMG-Y);PHOSPHORYLATION;METHYLATION AT ARG-26;MASS SPECTROMETRY strain: COP. tissue: Prostatic carcinoma. 2. Claus P. Submitted (2002-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM HMG-I) strain: Sprague-Dawley. tissue: Lung.

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