ELISA Kit for Rat High mobility group protein B2

Mfr.No.	E1476r
Alternative Names	High mobility group protein 2 ; HMG-2 ; Hmg2
Categories	Elisa
Function	DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS).
Specificity	Natural and recombinant Rat High mobility group protein B2
Subcellular Location	Nucleus Chromosome
Detection Range	0.156-10ng/mL
Entryname	HMGB2_RAT
Method Type	Sandwich
Platform	PF00505
Protein Name	High mobility group protein B2
Sensitivity	0.086ng/mL
Sequence	50: MGKGDPNKPR ; GKMSSYAFFV ; QTCREEHKKK ; HPDSSVNFAE ; FSKKCSERWK ; 100: TMSAKEKSKF ; EDLAKSDKAR ; YDREMKNYVP ; PKGDKKGKKK ; DPNAPKRPPS ; 150: AFFLFCSEHR ; PKIKSEHPGL ; SIGDTAKKLG ; EMWSEQSAKD ; KQPYEQKAAK ; 200: LKEKYEKDIA ; AYRAKGKSEV ; GKKGPGRPTG ; SKKKNEPEDE ; EEEEEEEDDE ; 210: DEEEEDEDEE ;
Sequence Length	210
String	P52925
Sub Unit	Component of the SET complex, which also contains SET, ANP32A, APEX1 and NME1. Directly interacts with SET. Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.

Reference	1. "Rat mRNA for chromosomal protein HMG2, complete cds." Yoshida M. Submitted (1996-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Fischer. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Spleen. tissue: Testis. tissue: Thymus.

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