JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Rat H/ACA ribonucleoprotein complex subunit 1

SKU : BHE13803943

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E12025r
Alternative Names	Nucleolar protein family A member 1 ; snoRNP protein GAR1 ; Nola1
Categories	Elisa
Function	Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ("psi") residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Specificity	Natural and recombinant Rat H/ACA ribonucleoprotein complex subunit 1
Subcellular Location	Nucleus nucleolus Nucleus Cajal body Also localized to Cajal bodies (coiled bodies).
Detection Range	0.312-20ng/ml
Entryname	GAR1_RAT
Method Type	Sandwich
Platform	PF04410
Protein Name	H/ACA ribonucleoprotein complex subunit 1
Sensitivity	0.162ng/mL
Sequence	50: MSFRGGGRGG ; FNRGGGGGGF ; NRGGGSNNHF ; RGGGGGGGGG ; GNFRGGGRGG ; 100: FGRGGGRGGF ; NKFQDQGPPE ; RVVLLGEFMH ; PCEDDIVCKC ; TTEENKVPYF ; 150: NAPVYLENKE ; QIGKVDEIFG ; QLRDFYFSVK ; LSENMKASSF ; KKLQKFYIDP ; 200: YKLLPLQRFL ; PRPPGEKGPP ; RGGGGGGGGG ; RGGRGGGRGG ; GGRGGGRGGG ; 226: FRGGRGGGGG ; FRGGRGGGGG ; FRGRGH
Sequence Length	226
String	Q6AYA1
Sub Unit	Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which contains NHP2/NOLA2, GAR1/NOLA1, NOP10/NOLA3, and DKC1/NOLA4, which is presumed to be the catalytic subunit. The complex contains a stable core formed by binding of one or two NOP10-DKC1 heterodimers to NHP2; GAR1 subsequently binds to this core via DKC1. The complex binds a box H/ACA small nucleolar RNA (snoRNA), which may target the specific site of modification within the RNA substrate. The complex also interacts with TERC, which contains a 3'-terminal domain related to the box H/ACA snoRNAs. Specific interactions with snoRNAs or TERC are mediated by GAR1 and NHP2. Associates with NOLC1/NOPP140. H/ACA snoRNPs interact with the SMN complex, consisting of SMN1 or SMN2, GEMIN2/SIP1, DDX20/GEMIN3, and GEMIN4. This is mediated by interaction between GAR1 and SMN1 or SMN2. The SMN complex may be required for correct assembly of the H/ACA snoRNP complex. Component of the telomerase holoenzyme complex at least composed of TERT, DKC1, WRAP53/TCAB1, NOP10, NHP2, GAR1, TEP1, EST1A, POT1 and a telomerase RNA template component (TERC).

Uniprot	Q6AYA1
Gene Name	Gar1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:499709
Unigene	Rn.15522

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Kidney.

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13803943	E12025r	96T	$796		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.