JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Rat GRB2-associated-binding protein 2

SKU : BHE13804309

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E2740r
Alternative Names	GRB2-associated binder 2 ; Growth factor receptor bound protein 2-associated protein 2
Categories	Elisa
Function	Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.
Specificity	Natural and recombinant Rat GRB2-associated-binding protein 2
Subcellular Location	Cytoplasm Cell membrane
Entryname	GAB2_RAT
Platform	PF00169
Protein Name	GRB2-associated-binding protein 2
Sequence	50: MSGGGGDDVV ; CTGWLRKSPP ; EKKLRRYAWK ; KRWFILRSGR ; MSGDPDVLEY ; 100: YKNEHSKKPL ; RIINLNFCEQ ; VDAGLTFNKK ; ELQDSFVFDI ; KTSERTFYLV ; 150: AETEADMNKW ; VQSICQICGF ; NQAEESTDSL ; RNLSSASHGP ; RSSPAEFSSS ; 200: QHLLRERKSS ; APSHSSQPTL ; FTFEPPMTSH ; MQPALSTSAP ; QEYLYLHQCI ; 250: SRRTENSRSA ; SFSQGTRQKS ; DTAVQKLAQS ; NGHCINGVSN ; QVHGFYSLPK ; 300: PSRHNTEFKD ; STYDLPRSLA ; SHGHTKSSLT ; GSETDNEDVY ; TFKMPSNTLC ; 350: REFGDLLVDN ; MDVPTTPLSA ; YQIPRTFTLD ; KNHNAMTVAT ; SGDSAIAPPP ; 400: RPPKPSQAET ; PRWGSPQQKP ; PIGENSRSVA ; ATIPRRNTLP ; AMDNSRLHRA ; 450: SSCETYEYPT ; RGSGESASWS ; AESPGKTAVG ; RSDSASSDEN ; YVPMNPGSST ; 500: LLAMERAGDN ; SQSAYIPMGP ; GPHHFDPLGY ; PSTALPIHRG ; PSRGSEIQPP ; 550: PVNRNLKPDR ; KAKPTPLDLR ; NNTVIDELPF ; KSPVTKSWSR ; INHTFNSSSS ; 600: QYCRPISTQS ; ITSTDSGDSE ; ENYVPMQNPV ; SASPVPSGTN ; SPAPRKSTGS ; 650: VDYLALDFQP ; GSPSPHRKPS ; TSSVTSDEKV ; DYVQVDKEKT ; QALQNTMQEW ; 665: TDVRQSSEPS ; KGAKL
Sequence Length	665
String	Q9EQH1
Sub Unit	Interacts with SHC1; may mediate interaction with receptors (By similarity). Interacts with SYK (By similarity). Interacts with PI-3 kinase (By similarity). Interacts with GRB2 (via SH3 2 domain) (By similarity). Interacts with PTPN11 (By similarity). Interacts with TNFRSF11A (via cytoplasmic domain) (By similarity). Interacts (phosphorylated) with 14-3-3 family proteins SFN, YWHAB, YWHAE, YWHAG, YWHAH, YWHAQ and YWHAZ; prevents interaction with GRB2 and attenuates GAB2 signaling.

Uniprot	Q9EQH1
Gene Name	Gab2
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:84477
Unigene	Rn.211990

Reference	1. "Identification of Gab2 as the major molecule responsible for EGF-induced PI3-kinase activation and DNA synthesis in rat hepatocytes." Kong M., Mounier C., Wu J., Posner B.I. Submitted (2001-08) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13804309	E2740r	96T	$796		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.