Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
Specificity
Natural and recombinant Rat Glycine N-methyltransferase
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];PROTEIN SEQUENCE OF 2-7;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT VAL-2
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 2-292 IN COMPLEXES WITH S-ADENOSYL-L-METHIONINE AND ACETATE;MUTAGENESIS OF TYR-34; ARG-176 AND TYR-221
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 2-292 IN COMPLEX WITH 5-METHYLTETRAHYDROFOLATE;ENZYME REGULATION
Reviews of ELISA Kit for Rat Glycine N-methyltransferase