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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Glutamate receptor 2

SKU : BHE13804479

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11294r
Alternative Names	AMPA-selective glutamate receptor 2 ; GluR-B ; GluR-K2 ; Glutamate receptor ionotropic ; AMPA 2 ; GluA2 ; Glur2
Categories	Elisa
Function	Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Specificity	Natural and recombinant Rat Glutamate receptor 2
Subcellular Location	Cell membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression.
Detection Range	0.156-10ng/mL
Entryname	GRIA2_RAT
Method Type	Sandwich
Platform	PF01094
Protein Name	Glutamate receptor 2
Sensitivity	0.091ng/mL
Sequence	50: MQKIMHISVL ; LSPVLWGLIF ; GVSSNSIQIG ; GLFPRGADQE ; YSAFRVGMVQ ; 100: FSTSEFRLTP ; HIDNLEVANS ; FAVTNAFCSQ ; FSRGVYAIFG ; FYDKKSVNTI ; 150: TSFCGTLHVS ; FITPSFPTDG ; THPFVIQMRP ; DLKGALLSLI ; EYYQWDKFAY ; 200: LYDSDRGLST ; LQAVLDSAAE ; KKWQVTAINV ; GNINNDKKDE ; TYRSLFQDLE ; 250: LKKERRVILD ; CERDKVNDIV ; DQVITIGKHV ; KGYHYIIANL ; GFTDGDLLKI ; 300: QFGGANVSGF ; QIVDYDDSLV ; SKFIERWSTL ; EEKEYPGAHT ; ATIKYTSALT ; 350: YDAVQVMTEA ; FRNLRKQRIE ; ISRRGNAGDC ; LANPAVPWGQ ; GVEIERALKQ ; 400: VQVEGLSGNI ; KFDQNGKRIN ; YTINIMELKT ; NGPRKIGYWS ; EVDKMVVTLT ; 450: ELPSGNDTSG ; LENKTVVVTT ; ILESPYVMMK ; KNHEMLEGNE ; RYEGYCVDLA ; 500: AEIAKHCGFK ; YKLTIVGDGK ; YGARDADTKI ; WNGMVGELVY ; GKADIAIAPL ; 550: TITLVREEVI ; DFSKPFMSLG ; ISIMIKKPQK ; SKPGVFSFLD ; PLAYEIWMCI ; 600: VFAYIGVSVV ; LFLVSRFSPY ; EWHTEEFEDG ; RETQSSESTN ; EFGIFNSLWF ; 650: SLGAFMQQGC ; DISPRSLSGR ; IVGGVWWFFT ; LIIISSYTAN ; LAAFLTVERM ; 700: VSPIESAEDL ; SKQTEIAYGT ; LDSGSTKEFF ; RRSKIAVFDK ; MWTYMRSAEP ; 750: SVFVRTTAEG ; VARVRKSKGK ; YAYLLESTMN ; EYIEQRKPCD ; TMKVGGNLDS ; 800: KGYGIATPKG ; SSLGNAVNLA ; VLKLNEQGLL ; DKLKNKWWYD ; KGECGSGGGD ; 850: SKEKTSALSL ; SNVAGVFYIL ; VGGLGLAMLV ; ALIEFCYKSR ; AEAKRMKVAK ; 883: NPQNINPSSS ; QNSQNFATYK ; EGYNVYGIES ; VKI
Sequence Length	883
String	P19491
Sub Unit	Homotetramer or heterotetramer of pore-forming glutamate receptor subunits. Tetramers may be formed by the dimerization of dimers. May interact with MPP4. Forms a ternary complex with GRIP1 and CSPG4 (By similarity). Interacts with CACNG2, PRKCABP, GRIP1 and GRIP2. Interacts with NSF via its C-terminus. Part of a complex containing GRIA2, NSF and NAPA and/or NAPB. Interacts with PICK1 (via PDZ domain) (By similarity). Interacts with GRIA1 and SYNDIG1 (By similarity). Interacts with LRFN1. Found in a complex with GRIA1, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8. Interacts with CACNG5.

Uniprot	P19491
Gene Name	Gria2
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:29627
Unigene	Rn.91361

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804479	E11294r	96T	$796		Add to Cart

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