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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Free fatty acid receptor 4

SKU : BHE13804809

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15282r
Alternative Names	G-protein coupled receptor 120 ; Omega-3 fatty acid receptor 1 ; Gpr120 ; O3far1
Categories	Elisa
Function	Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
Specificity	Natural and recombinant Rat Free fatty acid receptor 4
Subcellular Location	Cell membrane Multi-pass membrane protein Colocalized with ARRB2 following DHA treatment.
Entryname	FFAR4_RAT
Platform	PF00001
Protein Name	Free fatty acid receptor 4
Sequence	50: MSPECAQTTG ; PGPSRTPDQV ; NRTHFPFFSD ; VKGDHRLVLS ; VLETTVLGLI ; 100: FVVSLLGNVC ; ALVLVVRRRR ; RGATVSLVLN ; LFCADLLFTS ; AIPLVLVVRW ; 150: TEAWLLGPVV ; CHLLFYVMTM ; SGSVTILTLA ; AVSLERMVCI ; VRLRRGLSGP ; 200: GRRTQAALLA ; FIWGYSALAA ; LPLCILFRVV ; PQRLPGGDQE ; IPICTLDWPN ; 250: RIGEISWDVF ; FVTLNFLVPG ; LVIVISYSKI ; LQITKASRKR ; LTLSLAYSES ; 300: HQIRVSQQDY ; RLFRTLFLLM ; VSFFIMWSPI ; IITILLILIQ ; NFRQDLVIWP ; 350: SLFFWVVAFT ; FANSALNPIL ; YNMSLFRSEW ; RKIFCCFFFP ; EKGAIFTETS ; 361: IRRNDLSVIS ; T
Sequence Length	361
Sub Unit	Interacts with ARRB2 following docosahexaenoic acid (DHA) stimulation.

Uniprot	Q2AC31
Gene Name	Ffar4
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:294075
Unigene	Rn.82501

Reference	1. "Cloning and characterization of rat GPR120." Yano T., Katsuma S., Hirasawa A., Tsujimoto G. Submitted (2005-03) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804809	E15282r	96T	$796		Add to Cart

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