ELISA Kit for Rat Dexamethasone-induced Ras-related protein 1

Mfr.No.	E1528r
Alternative Names	Dexras1
Categories	Elisa
Function	Small GTPase. Negatively regulates the transcription regulation activity of the APBB1/FE65-APP complex via its interaction with APBB1/FE65.
Specificity	Natural and recombinant Rat Dexamethasone-induced Ras-related protein 1
Subcellular Location	Cell membrane Lipid-anchor Cytoplasmic side Cytoplasm perinuclear region Nucleus
Detection Range	0.312-20ng/mL
Entryname	RASD1_RAT
Method Type	Sandwich
Platform	PF00071
Protein Name	Dexamethasone-induced Ras-related protein 1
Sensitivity	0.162ng/mL
Sequence	50: MKLAAMIKKM ; CPSDSELSIP ; AKNCYRMVIL ; GSSKVGKTAI ; VSRFLTGRFE ; 100: DAYTPTIEDF ; HRKFYSIRGE ; VYQLDILDTS ; GNHPFPAMRR ; LSILTGDVFI ; 150: LVFSLDNRDS ; FEEVQRLKQQ ; ILDTKSCLKN ; KTKENVDVPL ; VICGNKGDRD ; 200: FYREVEQREI ; EQLVGDDPQR ; CAYFEISAKK ; NSSLDQMFRA ; LFAMAKLPSE ; 250: MSPDLHRKVS ; VQYCDVLHKK ; ALRNKKLLRA ; GSGGGGDHGD ; AFGILAPFAR ; 280: RPSVHSDLMY ; IREKTSVSSQ ; AKDKERCVIS ;
Sequence Length	280
String	Q9JKF8
Sub Unit	Forms a ternary complex with CAPON and NOS1. Component of a complex, at least composed of APBB1, RASD1/DEXRAS1 and APP. Interacts with APBB1/FE65. Forms.

Reference	1. "Dexras1: a G protein specifically coupled to neuronal nitric oxide synthase via CAPON." Fang M., Jaffrey S.R., Sawa A., Ye K., Luo X., Snyder S.H. Neuron28:183-193(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH CAPON AND NOS1;TISSUE SPECIFICITY 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Testis. 3. "Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription." Lau K.-F., Chan W.-M., Perkinton M.S., Tudor E.L., Chang R.C.C., Chan H.-Y., McLoughlin D.M., Miller C.C.J. J. Biol. Chem.283:34728-34737(2008) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;IDENTIFICATION IN A COMPLEX WITH APBB1 AND APP;INTERACTION WITH APBB1;MUTAGENESIS OF ALA-178

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