ELISA Kit for Rat Delta-aminolevulinic acid dehydratase

Mfr.No.	E2082r
Alternative Names	Porphobilinogen synthase
Categories	Elisa
Function	Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
Specificity	Natural and recombinant Rat Delta-aminolevulinic acid dehydratase
Detection Range	0.156-10ng/mL
Entryname	HEM2_RAT
Method Type	Sandwich
Platform	PF00490
Protein Name	Delta-aminolevulinic acid dehydratase
Sensitivity	0.078ng/mL
Sequence	50: MHHQSVLHSG ; YFHPLLRAWQ ; TTPSTVSATN ; LIYPIFVTDV ; PDDVQPIASL ; 100: PGVARYGVNQ ; LEEMLRPLVE ; AGLRCVLIFG ; VPSRVPKDEQ ; GSAADSEDSP ; 150: TIEAVRLLRK ; TFPTLLVACD ; VCLCPYTSHG ; HCGLLSENGA ; FLAEESRQRL ; 200: AEVALAYAKA ; GCQVVAPSDM ; MDGRVEAIKA ; ALLKHGLGNR ; VSVMSYSAKF ; 250: ASCFYGPFRD ; AAQSSPAFGD ; RRCYQLPPGA ; RGLALRAVAR ; DIQEGADILM ; 300: VKPGLPYLDM ; VQEVKDKHPE ; LPLAVYQVSG ; EFAMLWHGAK ; AGAFDLRTAV ; 330: LESMTAFRRA ; GADIIITYFA ; PQLLKWLKEE ;
Sequence Length	330
String	P06214
Sub Unit	Homooctamer; active form. Homohexamer; low activity form.

Reference	1. "Nucleotide sequence of rat liver delta-aminolevulinic acid dehydratase cDNA." Bishop T.R., Frelin L.P., Boyer S.H. Nucleic Acids Res.14:10115-10115(1986) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Liver. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Prostate. 3. "Isolation of a rat liver delta-aminolevulinate dehydrase (ALAD) cDNA clone: evidence for unequal ALAD gene dosage among inbred mouse strains." Bishop T.R., Cohen P.J., Boyer S.H., Noyes A.N., Frelin L.P. Proc. Natl. Acad. Sci. U.S.A.83:5568-5572(1986) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-45 4. Lubec G., Afjehi-Sadat L. Submitted (2006-11) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 56-84 AND 200-209;IDENTIFICATION BY MASS SPECTROMETRY strain: Sprague-Dawley. tissue: Spinal cord.

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