ELISA Kit for Rat Claudin-1

Mfr.No.	E9653r
Categories	Elisa
Function	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Specificity	Natural and recombinant Rat Claudin-1
Subcellular Location	Cell junction tight junction Cell membrane Multi-pass membrane protein
Detection Range	0.156-10ng/mL
Entryname	CLD1_RAT
Method Type	Sandwich
Platform	PF00822
Protein Name	Claudin-1
Sensitivity	0.078ng/mL
Sequence	50: MANAGLQLLG ; FILASLGWIG ; SIVSTALPQW ; KIYSYAGDNI ; VTAQAIYEGL ; 100: WMSCVSQSTG ; QIQCKVFDSL ; LNLNSTLQAT ; RALMVIGILL ; GLIAIFVSTI ; 150: GMKCMRCLED ; DEVQKMWMAV ; IGGIIFVISG ; LATLVATAWY ; GNRIVQEFYD ; 200: PMTPVNARYE ; FGQALFTGWA ; AASLCLLGGA ; LLSCSCPRKT ; TSYPTPRPYP ; 211: KPTPSSGKDY ; V
Sequence Length	211
String	P56745
Sub Unit	Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL.

Reference	1. "Claudin-1 is not restricted to tight junctions in the rat epididymis." Gregory M., Dufresne J., Hermo L., Cyr D. Endocrinology142:854-863(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ASP-23;SUBCELLULAR LOCATION;TISSUE SPECIFICITY strain: Sprague-Dawley. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Prostate.

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